PPP1R9B

Across TCGA patient cohorts, PPP1R9B mutation is significantly associated with the RNA expression of many other genes, with 603 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP1R9B-associated genes across cancer lineages are RPL22P5, CRABP2, and ATP6V0A1. Each is linked with PPP1R9B in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R9B-to-partner and partner-to-PPP1R9B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL22P5 grouped by PPP1R9B-low versus PPP1R9B-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R9B→partner) and Y-score (partner→PPP1R9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RPL22P5 →	+0.047	+3.362	.007	.006	3	2
UCEC	CRABP2 →	-1.253	-2.700	.006	.006	3	2
UCEC	ATP6V0A1 →	+0.389	+2.246	.003	.005	3	2
UCEC	ACOT7 →	+0.612	+2.238	.005	.006	3	2
CESC	RN7SL627P →	+0.150	+5.891	<.001	<.001	3	2
UCEC	SNORA10B →	+0.244	+2.709	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 603 associations by consensus.

RPL22P5 by PPP1R9B expression — SKCM

Explore this box plot interactively →