PPP1R9B

Across TCGA pan-cancer cohorts, PPP1R9B RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated PPP1R9B data layer compared with 4 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher PPP1R9B RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PPP1R9B expression acts as an unfavorable survival marker, although some lineages such as LUAD and KIRC show a favorable association.

MESO, UVM, and LIHC are the cancer types where PPP1R9B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.429	0.651	<.001	66	view →
UVM	DFS	Tertile	II,III,IV	0.409	0.748	.001	59	view →
LIHC	OS	Median	All	0.713	0.836	.001	52	view →
LUAD	OS	Median	III,IV	0.643	0.375	<.001	48	view →
KIRC	DFS	Quartile	IV	0.760	0.339	.006	33	view →
PAAD	OS	Tertile	II,III,IV	0.667	0.408	.006	30	view →
ACC	OS	Quartile	IV	0.276	0.935	.006	28	view →
KIRP	DFS	Quartile	III,IV	0.480	0.822	.016	23	view →
COAD	DFS	Tertile	II,III,IV	0.399	0.717	.013	19	view →
LAML	DFS	Median	All	0.358	0.550	.006	18	view →
HNSC	OS	Median	All	0.618	0.799	.007	13	view →
ESCA	DFS	Median	II,III,IV	1.000	0.399	.013	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

PPP1R9B–MESO (OS)

Open the MESO breakdown →