PPP1R9B

Across TCGA cell cohorts, PPP1R9B mutation is significantly associated with the RNA expression of many other genes, with 47 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PPP1R9B-associated genes across cancer lineages are ITGAD, BPIFB2, and FTHL17. Each is linked with PPP1R9B in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R9B-to-partner and partner-to-PPP1R9B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ITGAD grouped by PPP1R9B-low versus PPP1R9B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R9B→partner) and Y-score (partner→PPP1R9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ITGAD →	+0.015	+4.095	<.001	.009	3	2
BLOOD_Leukemia	BPIFB2 →	+0.024	+3.696	.004	.006	3	2
LARGE_INTESTINE	FTHL17 →	+0.060	+4.415	<.001	.007	3	1
LARGE_INTESTINE	SPIC →	+0.296	+4.095	<.001	.009	3	1
LARGE_INTESTINE	OR2V2 →	+0.017	+4.095	<.001	.009	3	1
LARGE_INTESTINE	BPY2 →	+0.022	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

ITGAD by PPP1R9B expression — LARGE_INTESTINE

Explore this box plot interactively →