PPP1R9A

Across TCGA pan-cancer cohorts, PPP1R9A Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated PPP1R9A data layer compared with 18 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in thymoma (THYM), where higher PPP1R9A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated PPP1R9A expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

THYM, UCEC, and BRCA are the cancer types where PPP1R9A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Median	III,IV	0.103	0.944	<.001	42	view →
UCEC	DFS	Median	II,III,IV	1.000	0.430	.004	34	view →
BRCA	OS	Median	All	0.843	0.963	.002	10	view →
SARC	DFS	Median	All	0.121	0.591	.042	6	view →
ESCA	OS	Median	All	0.453	0.703	.030	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

PPP1R9A–THYM (OS)

Open the THYM breakdown →