PPP1R9A

Across TCGA pan-cancer cohorts, PPP1R9A mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated PPP1R9A data layer compared with 18 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher PPP1R9A mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated PPP1R9A expression acts as an unfavorable survival marker, although some lineages such as GBM and LUAD show a favorable association.

GBM, LUAD, and HNSC are the cancer types where PPP1R9A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	DFS	Median	All	0.806	0.630	.002	14	view →
LUAD	OS	Tertile	II,III,IV	0.770	0.387	.010	8	view →
HNSC	OS	Median	III,IV	0.950	0.769	.021	6	view →
PDAC	OS	Tertile	II,III,IV	0.943	0.788	.029	5	view →
UCEC	DFS	Quartile	All	1.000	0.846	.022	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

PPP1R9A–GBM (DFS)

Open the GBM breakdown →