PPP1R9A

Across TCGA patient cohorts, PPP1R9A mutation is significantly associated with the RNA expression of many other genes, with 6,527 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP1R9A-associated genes across cancer lineages are ALYREF, RNF168, and C2orf69. Each is linked with PPP1R9A in more than 3 cancer types. Because this analysis shows association rather than direction, both PPP1R9A-to-partner and partner-to-PPP1R9A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ALYREF grouped by PPP1R9A-low versus PPP1R9A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R9A→partner) and Y-score (partner→PPP1R9A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ALYREF →	+0.509	+1.925	<.001	<.001	3	4
UCEC	RNF168 →	+0.343	+1.461	.003	<.001	3	4
UCEC	C2orf69 →	+0.336	+1.684	.004	.001	3	4
UCEC	MTFR2 →	+0.450	+1.760	.001	<.001	3	4
READ	MIR4774 →	+0.841	+6.257	<.001	.001	3	3
UCEC	UQCRC1 →	+0.359	+2.448	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,527 associations by consensus.

ALYREF by PPP1R9A expression — UCEC

Explore this box plot interactively →