PPP1R9A

Across TCGA patient cohorts, PPP1R9A mutation is significantly associated with the total protein of many other genes, with 64 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP1R9A-associated genes across cancer lineages are GAPDH, STAT3_pY705, and Cyclin-B1. Each is linked with PPP1R9A in more than 3 cancer types. Because this analysis shows association rather than direction, both PPP1R9A-to-partner and partner-to-PPP1R9A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDH grouped by PPP1R9A-low versus PPP1R9A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R9A→partner) and Y-score (partner→PPP1R9A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GAPDH →	+0.376	+1.662	.012	.009	3	4
UCEC	STAT3_pY705 →	-0.380	-2.044	<.001	<.001	3	3
UCEC	Cyclin-B1 →	+0.676	+2.044	<.001	<.001	3	3
LUSC	FASN →	+0.445	+3.584	.010	.002	3	2
LUSC	MSH2 →	+0.247	+1.594	.042	.043	3	2
UCEC	eEF2 →	+0.243	+2.222	.015	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 64 associations by consensus.

GAPDH by PPP1R9A expression — UCEC

Explore this box plot interactively →