PPP1R9A

Across TCGA cell cohorts, PPP1R9A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,431 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PPP1R9A-associated GO terms across cancer lineages are Positive regulation of DNA recombination, Negative regulation of vitamin D biosynthetic process, and Regulation of vitamin D biosynthetic process. Each is linked with PPP1R9A in more than 11 cancer types. Because this analysis shows association rather than direction, both PPP1R9A-to-partner and partner-to-PPP1R9A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA recombination grouped by PPP1R9A-low versus PPP1R9A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R9A→partner) and Y-score (partner→PPP1R9A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of DNA recombination →	+0.090	+1.039	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Negative regulation of vitamin D biosynthetic process →	-1.053	-1.761	.005	<.001	3	11
BONE	Regulation of vitamin D biosynthetic process →	-1.546	-1.349	<.001	<.001	3	11
LIVER	Positive regulation of double-strand break repair →	+0.099	+2.298	<.001	<.001	3	11
BLOOD_Lymphoma	Heterochromatin organization →	+0.058	+0.675	<.001	.006	3	10
BONE	Regulation of transcription by RNA polymerase I →	+0.178	+1.552	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,431 associations by consensus.

Positive regulation of DNA recombination by PPP1R9A expression — BONE

Explore this box plot interactively →