PPP1R9A

Across TCGA cell cohorts, PPP1R9A mutation is significantly associated with the RNA expression of many other genes, with 915 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PPP1R9A-associated genes across cancer lineages are TGM7, SMIM8, and METTL16. Each is linked with PPP1R9A in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R9A-to-partner and partner-to-PPP1R9A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TGM7 grouped by PPP1R9A-low versus PPP1R9A-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R9A→partner) and Y-score (partner→PPP1R9A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	TGM7 →	+0.004	+4.369	<.001	.008	3	2
SKIN	SMIM8 →	+0.425	+2.743	<.001	.001	3	2
SKIN	METTL16 →	+0.472	+3.257	<.001	.002	3	2
SKIN	FAM117B →	+0.457	+2.129	.002	.007	3	2
LARGE_INTESTINE	ZNF691 →	+0.361	+2.829	.009	<.001	3	2
SKIN	P4HTM →	+1.127	+3.160	.002	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 915 associations by consensus.

TGM7 by PPP1R9A expression — SOFT_TISSUE

Explore this box plot interactively →