PPP1R9A-AS1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, PPP1R9A-AS1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of PPP1R9A-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where PPP1R9A-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types PPP1R9A-AS1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, THCA, and KIRC are the cancer types where PPP1R9A-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PPP1R9A-AS1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KICHFemaleAll−0.130<.0016view →
THCAFemaleAll−0.038<.0015view →
KIRCAllII,III,IV−0.038<.0015view →
LUSCFemaleAll−0.040.0023view →
BRCAAllIII,IV−0.095<.0012view →
READAllIII,IV−0.035.0192view →
COADAllII,III,IV−0.011.0072view →
LUADFemaleIII,IV−0.045.0181view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

PPP1R9A-AS1–KICH

Tumor-vs-normal expression box plot for PPP1R9A-AS1 RNA in KICH.

Open the KICH breakdown →

Exploration