PPP1R42

Across TCGA patient cohorts, PPP1R42 protein abundance is significantly associated with the RNA expression of many other genes, with 193 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPP1R42-associated genes across cancer lineages are TNFSF13B, CCL8, and CD86. Each is linked with PPP1R42 in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R42-to-partner and partner-to-PPP1R42 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP1R42 versus TNFSF13B in BRCA, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R42→partner) and Y-score (partner→PPP1R42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TNFSF13B →	+0.792	+1.089	<.001	<.001	3	1
BRCA	CCL8 →	+1.609	+0.922	.003	.006	3	1
BRCA	CD86 →	+0.703	+0.765	<.001	.006	3	1
BRCA	HEMK1 →	-0.740	-0.937	.008	.001	3	1
BRCA	GBP1 →	+1.530	+0.935	.003	.003	3	1
BRCA	MRPS12 →	+0.655	+0.676	.004	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 193 associations by consensus.

PPP1R42 vs TNFSF13B — BRCA

Explore this scatter interactively →