PPP1R42

Across TCGA cell cohorts, PPP1R42 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,658 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PPP1R42-associated GO terms across cancer lineages are Protein localization to ciliary membrane, Platelet morphogenesis, and Positive regulation of translational initiation. Each is linked with PPP1R42 in more than 6 cancer types. Because this analysis shows association rather than direction, both PPP1R42-to-partner and partner-to-PPP1R42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to ciliary membrane grouped by PPP1R42-low versus PPP1R42-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R42→partner) and Y-score (partner→PPP1R42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Protein localization to ciliary membrane →	+0.063	+0.327	<.001	<.001	2	7
SOFT_TISSUE	Platelet morphogenesis →	+0.074	+0.308	<.001	<.001	3	6
CNS	Positive regulation of translational initiation →	+0.063	+0.308	<.001	<.001	3	6
SOFT_TISSUE	Glycoprotein catabolic process →	+0.101	+0.362	<.001	.002	3	5
CNS	Regulation of glycolytic process through fructose-6-phosphate →	+0.046	+0.218	.007	.004	2	6
CNS	Negative regulation of glycolytic process through fructose-6-phosphate →	+0.046	+0.218	.007	.004	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,658 associations by consensus.

Protein localization to ciliary membrane by PPP1R42 expression — CNS

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