Across TCGA cell cohorts, PPP1R3G mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible PPP1R3G-associated genes across cancer lineages are RAX, LCE3D, and ACER1. Each is linked with PPP1R3G in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R3G-to-partner and partner-to-PPP1R3G results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R3G→partner) and Y-score (partner→PPP1R3G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	RAX →	+0.171	+3.662	.002	.009	3	1
OVARY	LCE3D →	+0.107	+4.339	<.001	.001	3	1
OVARY	ACER1 →	+0.043	+3.938	<.001	.005	3	1
OVARY	SALL3 →	+0.122	+4.095	<.001	.003	3	1
OVARY	CACNG5 →	+0.035	+4.095	<.001	.003	3	1
OVARY	CMA1 →	+0.054	+3.791	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

PPP1R3G survival (RNA) · tumor vs normal (RNA) · all PPP1R3G data types