PPP1R3F

Across TCGA patient cohorts, PPP1R3F protein abundance is significantly associated with the RNA expression of many other genes, with 6,286 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPP1R3F-associated genes across cancer lineages are APLP1, HPN, and PEX5L. Each is linked with PPP1R3F in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R3F-to-partner and partner-to-PPP1R3F results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP1R3F versus APLP1 in GBM, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R3F→partner) and Y-score (partner→PPP1R3F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	APLP1 →	+0.547	+0.206	.004	.002	3	2
PDAC	HPN →	+1.279	+0.332	<.001	.001	3	2
GBM	PEX5L →	+1.213	+0.273	<.001	<.001	3	2
GBM	SLC8A2 →	+0.773	+0.232	<.001	<.001	3	2
PDAC	FCF1 →	-0.302	-0.354	.005	.002	3	2
PDAC	MAPK8IP1 →	+0.516	+0.319	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,286 associations by consensus.

PPP1R3F vs APLP1 — GBM

Explore this scatter interactively →