PPP1R3E

Across TCGA patient cohorts, PPP1R3E protein abundance is significantly associated with the RNA expression of many other genes, with 5,789 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PPP1R3E-associated genes across cancer lineages are MOB2, ARHGEF37, and RCN1. Each is linked with PPP1R3E in more than 2 cancer types. Because this analysis shows association rather than direction, both PPP1R3E-to-partner and partner-to-PPP1R3E results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP1R3E versus MOB2 in UCEC, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R3E→partner) and Y-score (partner→PPP1R3E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MOB2 →	+0.974	+0.728	.004	.001	3	3
HNSC	ARHGEF37 →	+1.188	+0.810	.001	.008	3	3
BRCA	RCN1 →	-1.517	-0.512	.001	.001	3	3
BRCA	RUFY4 →	-0.738	-0.354	.001	.004	3	3
UCEC	SDR39U1 →	+0.597	+0.867	.003	.008	3	2
UCEC	RASL12 →	+2.252	+0.826	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,789 associations by consensus.

PPP1R3E vs MOB2 — UCEC

Explore this scatter interactively →