PPP1R3D

Across TCGA patient cohorts, PPP1R3D protein abundance is significantly associated with the RNA expression of many other genes, with 7,148 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPP1R3D-associated genes across cancer lineages are GID8, OSBPL2, and SLCO5A1. Each is linked with PPP1R3D in more than 4 cancer types. Because this analysis shows association rather than direction, both PPP1R3D-to-partner and partner-to-PPP1R3D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP1R3D versus GID8 in LUAD, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R3D→partner) and Y-score (partner→PPP1R3D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GID8 →	+0.524	+0.325	<.001	<.001	3	5
COAD	OSBPL2 →	+0.583	+0.413	<.001	.001	3	5
UCEC	SLCO5A1 →	-1.073	-0.195	<.001	.007	3	4
PDAC	HCAR2 →	+0.994	+0.254	.005	.005	3	4
LSCC	STAU1 →	+0.528	+0.326	<.001	<.001	3	4
LSCC	ARHGAP18 →	-0.460	-0.394	.003	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,148 associations by consensus.

PPP1R3D vs GID8 — LUAD

Explore this scatter interactively →