PPP1R3D

Across TCGA cell cohorts, PPP1R3D RNA expression is significantly associated with the go_rna of many other GO terms, with 4,704 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PPP1R3D-associated GO terms across cancer lineages are Endosome organization, Cellular response to unfolded protein, and Cellular response to topologically incorrect protein. Each is linked with PPP1R3D in more than 12 cancer types. Because this analysis shows association rather than direction, both PPP1R3D-to-partner and partner-to-PPP1R3D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosome organization grouped by PPP1R3D-low versus PPP1R3D-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R3D→partner) and Y-score (partner→PPP1R3D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Endosome organization →	+0.044	+0.489	<.001	.001	3	13
PANCREAS	Cellular response to unfolded protein →	+0.105	+0.707	.001	.001	3	13
STOMACH	Cellular response to topologically incorrect protein →	+0.064	+0.911	.002	<.001	3	13
LUNG_NSCLC_LUSC	Endoplasmic reticulum unfolded protein response →	+0.100	+0.714	.002	.003	2	13
LUNG_SCLC	Protein targeting to lysosome involved in chaperone-mediated autophagy →	+0.178	+0.866	<.001	.002	3	12
PANCREAS	Late endosome to vacuole transport →	+0.075	+0.645	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,704 associations by consensus.

Endosome organization by PPP1R3D expression — SOFT_TISSUE

Explore this box plot interactively →