PPP1R3C

Across TCGA cell cohorts, PPP1R3C RNA expression is significantly associated with the go_rna of many other GO terms, with 3,949 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PPP1R3C-associated GO terms across cancer lineages are Elastin metabolic process, Negative regulation of protein catabolic process, and Golgi vesicle transport. Each is linked with PPP1R3C in more than 10 cancer types. Because this analysis shows association rather than direction, both PPP1R3C-to-partner and partner-to-PPP1R3C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Elastin metabolic process grouped by PPP1R3C-low versus PPP1R3C-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R3C→partner) and Y-score (partner→PPP1R3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Elastin metabolic process →	+0.358	+2.651	<.001	<.001	3	11
STOMACH	Negative regulation of protein catabolic process →	+0.071	+1.523	<.001	<.001	3	10
BONE	Golgi vesicle transport →	+0.083	+2.839	<.001	<.001	3	9
STOMACH	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.066	+1.735	<.001	<.001	3	9
SOFT_TISSUE	Negative regulation of protein maturation →	+0.214	+1.649	.002	.006	3	9
BONE	COPII-coated vesicle cargo loading →	+0.119	+2.444	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,949 associations by consensus.

Elastin metabolic process by PPP1R3C expression — BONE

Explore this box plot interactively →