PPP1R3A

Across TCGA patient cohorts, PPP1R3A RNA expression is significantly associated with the protein abundance of many other proteins, with 6,495 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PPP1R3A-associated proteins across cancer lineages are SMARCC2_S283, WDR11, and WDR43_T656. Each is linked with PPP1R3A in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R3A-to-partner and partner-to-PPP1R3A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP1R3A versus SMARCC2_S283 in BRCA, with a Pearson correlation of -0.21.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R3A→partner) and Y-score (partner→PPP1R3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SMARCC2_S283 →	-0.417	-0.008	.008	.007	3	2
GBM	WDR11 →	-0.140	-0.015	.004	.008	3	2
HNSC	WDR43_T656 →	-0.576	-1.002	.001	.002	3	2
BRCA	THRAP3_S939 →	-0.425	-0.012	.002	.004	3	2
PDAC	PRKCI_S247 →	-0.638	-0.014	.007	.003	3	2
HNSC	PRUNE2_S699 →	+1.661	+1.447	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,495 associations by consensus.

PPP1R3A vs SMARCC2_S283 — BRCA

Explore this scatter interactively →