PPP1R3A

Across TCGA patient cohorts, PPP1R3A RNA expression is significantly associated with the go_rna of many other GO terms, with 6,508 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PPP1R3A-associated GO terms across cancer lineages are Regulation of muscle system process, Regulation of organelle assembly, and Pallium development. Each is linked with PPP1R3A in more than 9 cancer types. Because this analysis shows association rather than direction, both PPP1R3A-to-partner and partner-to-PPP1R3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of muscle system process grouped by PPP1R3A-low versus PPP1R3A-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R3A→partner) and Y-score (partner→PPP1R3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of muscle system process →	+0.049	+0.039	<.001	<.001	3	10
STAD	Regulation of organelle assembly →	+0.074	+0.042	<.001	<.001	3	10
STAD	Pallium development →	+0.059	+0.040	<.001	<.001	3	10
STAD	Cellular response to UV →	+0.075	+0.041	<.001	<.001	3	10
UCS	Striated muscle contraction →	+0.085	+1.009	<.001	<.001	3	10
STAD	Establishment of protein localization to membrane →	+0.081	+0.041	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,508 associations by consensus.

Regulation of muscle system process by PPP1R3A expression — STAD

Explore this box plot interactively →