PPP1R3A

Across TCGA cell cohorts, PPP1R3A RNA expression is significantly associated with the RNA expression of many other genes, with 1,107 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible PPP1R3A-associated genes across cancer lineages are MINAR2, GFRAL, and SIGLEC8. Each is linked with PPP1R3A in more than 3 cancer types. Because this analysis shows association rather than direction, both PPP1R3A-to-partner and partner-to-PPP1R3A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP1R3A versus MINAR2 in STOMACH, with a Pearson correlation of 0.23.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R3A→partner) and Y-score (partner→PPP1R3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	MINAR2 →	+0.122	+1.166	.006	<.001	3	4
LUNG_NSCLC_LUSC	GFRAL →	+0.014	+0.078	<.001	<.001	3	4
UPPER_AERODIGESTIVE_TRACT	SIGLEC8 →	+0.062	+0.079	.005	<.001	3	4
BREAST	PNLIPRP1 →	+0.212	+0.018	.006	.002	3	3
LUNG_NSCLC_LUSC	USP29 →	+0.046	+0.052	.003	.003	3	3
UPPER_AERODIGESTIVE_TRACT	GPR119 →	+0.074	+0.029	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,107 associations by consensus.

PPP1R3A vs MINAR2 — STOMACH

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