PPP1R35

Across TCGA pan-cancer cohorts, PPP1R35 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated PPP1R35 data layer compared with 21 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in thyroid carcinoma (THCA), where higher PPP1R35 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated PPP1R35 expression acts as an unfavorable survival marker.

THCA and COAD are the cancer types where PPP1R35 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Median	All	0.098	0.941	<.001	42	view →
COAD	OS	Median	All	0.056	0.871	<.001	24	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

PPP1R35–THCA (OS)

Open the THCA breakdown →