PPP1R35

Across TCGA pan-cancer cohorts, PPP1R35 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated PPP1R35 data layer compared with 21 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher PPP1R35 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated PPP1R35 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

LUAD and CCRCC are the cancer types where PPP1R35 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	All	0.306	0.758	.008	6	view →
CCRCC	DFS	Median	All	0.851	0.306	.045	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

PPP1R35–LUAD (OS)

Open the LUAD breakdown →