PPP1R35-AS1

Across TCGA pan-cancer cohorts, PPP1R35-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated PPP1R35-AS1 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher PPP1R35-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PPP1R35-AS1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and DLBC show a favorable association.

BRCA, ACC, and PAAD are the cancer types where PPP1R35-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Tertile	III,IV	0.710	0.883	.001	68	view →
ACC	DFS	Tertile	All	0.308	0.704	<.001	58	view →
PAAD	OS	Median	All	0.676	0.377	<.001	47	view →
LGG	DFS	Tertile	All	0.686	0.836	<.001	37	view →
KIRC	DFS	Median	III,IV	0.332	0.573	<.001	24	view →
DLBC	DFS	Median	II,III,IV	0.938	0.522	.008	19	view →
ESCA	DFS	Tertile	III,IV	0.294	0.549	.010	15	view →
UVM	OS	Median	III,IV	0.296	1.000	.005	13	view →
CESC	OS	Median	All	0.863	0.733	.002	12	view →
THYM	DFS	Quartile	All	0.970	0.798	.018	11	view →
LUSC	OS	Quartile	All	0.924	0.681	.007	11	view →
GBM	DFS	Quartile	All	0.510	0.194	.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

PPP1R35-AS1–BRCA (DFS)

Open the BRCA breakdown →