PPP1R32

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PPP1R32 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,623 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PPP1R32-associated GO terms across cancer lineages are Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway, [4Fe-4S] cluster assembly, and Pyrimidine nucleoside diphosphate biosynthetic process. Each is linked with PPP1R32 in more than 13 cancer types. Because this analysis shows association rather than direction, both PPP1R32-to-partner and partner-to-PPP1R32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway grouped by PPP1R32-low versus PPP1R32-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R32→partner) and Y-score (partner→PPP1R32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
URINARY_TRACTCo-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →+0.096+0.702<.001<.001314
KIDNEY[4Fe-4S] cluster assembly →-0.123-0.835<.001<.001314
LUNG_NSCLC_LUSCPyrimidine nucleoside diphosphate biosynthetic process →-0.162-0.550<.001.004313
OESOPHAGUSMaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →-0.130-0.687.002.006313
UPPER_AERODIGESTIVE_TRACTCilium movement →-0.056-0.654.007<.001312
URINARY_TRACTEndonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →-0.140-1.107.001<.001312
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,623 associations by consensus.

Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway by PPP1R32 expression — URINARY_TRACT

Box plot of Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway in PPP1R32-low vs PPP1R32-high samples in URINARY_TRACT.

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Exploration