Across TCGA cell cohorts, PPP1R26 mutation is significantly associated with the RNA expression of many other genes, with 2,139 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PPP1R26-associated genes across cancer lineages are SGSM3, LLGL1, and EDEM1. Each is linked with PPP1R26 in more than 2 cancer types. Because this analysis shows association rather than direction, both PPP1R26-to-partner and partner-to-PPP1R26 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R26→partner) and Y-score (partner→PPP1R26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SGSM3 →	+0.650	+2.364	.001	<.001	3	3
LARGE_INTESTINE	LLGL1 →	+0.741	+2.767	.001	<.001	3	3
LARGE_INTESTINE	EDEM1 →	+0.528	+3.169	.003	.006	3	3
LARGE_INTESTINE	SLBP →	+0.610	+3.129	<.001	<.001	3	3
LARGE_INTESTINE	SHMT1 →	+0.806	+3.043	<.001	<.001	3	3
LARGE_INTESTINE	SHPK →	+0.603	+3.169	.002	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,139 associations by consensus.

Exploration

PPP1R26 survival (RNA) · tumor vs normal (RNA) · all PPP1R26 data types