PPP1R1B

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PPP1R1B RNA expression is significantly associated with the protein abundance of many other proteins, with 12,858 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPP1R1B-associated proteins across cancer lineages are PPP1R1B_S46, PPP1R1B_T34, and PPP1R1B_S58. Each is linked with PPP1R1B in more than 6 cancer types. Because this analysis shows association rather than direction, both PPP1R1B-to-partner and partner-to-PPP1R1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP1R1B versus PPP1R1B_S46 in UCEC, with a Pearson correlation of 0.77.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R1B→partner) and Y-score (partner→PPP1R1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPPP1R1B_S46 →+1.213+2.268<.001<.00137
OVPPP1R1B_T34 →+2.897+3.001<.001<.00137
BRCAPPP1R1B_S58 →+2.680+4.320<.001<.00136
GBMPPP1R1B_T75 →+1.213+2.641<.001<.00136
PDACSH3BGRL2 →+0.441+1.365.001<.00135
BRCAPPP1R1B_S102 →+1.123+2.242<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,858 associations by consensus.

PPP1R1B vs PPP1R1B_S46 — UCEC

Per-sample scatter of PPP1R1B vs PPP1R1B_S46 in UCEC (Pearson r = 0.77).

Explore this scatter interactively →

Exploration