PPP1R1B

Across TCGA cell cohorts, PPP1R1B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,754 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PPP1R1B-associated GO terms across cancer lineages are Blood coagulation, intrinsic pathway, Regulation of DNA repair, and Regulation of blood pressure. Each is linked with PPP1R1B in more than 9 cancer types. Because this analysis shows association rather than direction, both PPP1R1B-to-partner and partner-to-PPP1R1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Blood coagulation, intrinsic pathway grouped by PPP1R1B-low versus PPP1R1B-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R1B→partner) and Y-score (partner→PPP1R1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Blood coagulation, intrinsic pathway →	-0.213	-3.248	.004	<.001	2	10
BONE	Regulation of DNA repair →	+0.074	+1.238	<.001	<.001	3	8
BONE	Regulation of blood pressure →	-0.112	-1.333	.003	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	ATP synthesis coupled electron transport →	+0.081	+0.484	<.001	.002	3	7
UPPER_AERODIGESTIVE_TRACT	Mitochondrial ATP synthesis coupled electron transport →	+0.081	+0.484	<.001	.002	3	7
SOFT_TISSUE	Regulation of coagulation →	-0.120	-0.480	<.001	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,754 associations by consensus.

Blood coagulation, intrinsic pathway by PPP1R1B expression — BREAST

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