PPP1R1AP1

Across TCGA patient cohorts, PPP1R1AP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,562 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PPP1R1AP1-associated GO terms across cancer lineages are Methylation, Regulation of embryonic development, and mRNA 3'-end processing. Each is linked with PPP1R1AP1 in more than 18 cancer types. Because this analysis shows association rather than direction, both PPP1R1AP1-to-partner and partner-to-PPP1R1AP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Methylation grouped by PPP1R1AP1-low versus PPP1R1AP1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R1AP1→partner) and Y-score (partner→PPP1R1AP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Methylation →	+0.056	+0.309	<.001	<.001	3	19
STAD	Regulation of embryonic development →	+0.048	+0.198	<.001	<.001	3	17
ESCA	mRNA 3'-end processing →	+0.073	+0.326	<.001	<.001	3	16
ESCA	Positive regulation of transcription elongation by RNA polymerase II →	+0.061	+0.358	<.001	<.001	3	16
ESCA	snRNA metabolic process →	+0.072	+0.343	<.001	<.001	3	16
ESCA	Peptidyl-lysine modification →	+0.060	+0.297	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,562 associations by consensus.

Methylation by PPP1R1AP1 expression — ESCA

Explore this box plot interactively →