PPP1R17

Across TCGA patient cohorts, PPP1R17 mutation is significantly associated with the RNA expression of many other genes, with 131 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP1R17-associated genes across cancer lineages are RN7SL563P, MIR4456, and COPS5P1. Each is linked with PPP1R17 in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R17-to-partner and partner-to-PPP1R17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL563P grouped by PPP1R17-low versus PPP1R17-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R17→partner) and Y-score (partner→PPP1R17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RN7SL563P →	+0.117	+5.149	<.001	.003	3	2
BRCA	MIR4456 →	+0.552	+8.055	<.001	.007	3	2
HNSC	COPS5P1 →	+0.076	+4.508	<.001	.005	3	2
UCEC	MIR548AG2 →	+0.241	+5.060	<.001	.001	3	2
HNSC	PYDC2 →	+0.231	+4.372	.006	.007	3	2
UCEC	RNA5SP410 →	+0.888	+2.789	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 131 associations by consensus.

RN7SL563P by PPP1R17 expression — LIHC

Explore this box plot interactively →