PPP1R16B

Across TCGA patient cohorts, PPP1R16B RNA expression is significantly associated with the protein abundance of many other proteins, with 30,461 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPP1R16B-associated proteins across cancer lineages are SEPTIN6_S388, GNG2, and PIP4K2A. Each is linked with PPP1R16B in more than 8 cancer types. Because this analysis shows association rather than direction, both PPP1R16B-to-partner and partner-to-PPP1R16B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP1R16B versus SEPTIN6_S388 in GBM, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R16B→partner) and Y-score (partner→PPP1R16B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SEPTIN6_S388 →	+0.796	+1.765	<.001	<.001	3	9
GBM	GNG2 →	+0.731	+1.680	<.001	<.001	3	9
LSCC	PIP4K2A →	+0.461	+1.120	<.001	<.001	3	9
LSCC	RTN1 →	+0.484	+1.001	<.001	<.001	3	8
LSCC	SEPTIN1_S315 →	+1.313	+1.215	<.001	<.001	3	8
LSCC	SEPTIN6 →	+0.625	+1.216	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 30,461 associations by consensus.

PPP1R16B vs SEPTIN6_S388 — GBM

Explore this scatter interactively →