PPP1R16B

Across TCGA patient cohorts, PPP1R16B mutation is significantly associated with the RNA expression of many other genes, with 2,745 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP1R16B-associated genes across cancer lineages are PCGF7P, FAM177A1P1, and POLE2. Each is linked with PPP1R16B in more than 2 cancer types. Because this analysis shows association rather than direction, both PPP1R16B-to-partner and partner-to-PPP1R16B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCGF7P grouped by PPP1R16B-low versus PPP1R16B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R16B→partner) and Y-score (partner→PPP1R16B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PCGF7P →	+0.233	+3.415	<.001	.004	3	3
SKCM	FAM177A1P1 →	+0.041	+1.825	.006	.008	3	3
UCEC	POLE2 →	+0.540	+2.072	<.001	<.001	3	3
SKCM	RNASEH2A →	+0.437	+2.764	.004	.002	3	3
UCEC	CACTIN →	+0.326	+2.061	<.001	<.001	3	3
UCEC	DAD1 →	+0.333	+2.093	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,745 associations by consensus.

PCGF7P by PPP1R16B expression — COAD

Explore this box plot interactively →