PPP1R16B

Across TCGA cell cohorts, PPP1R16B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,610 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PPP1R16B-associated GO terms across cancer lineages are Positive regulation of DNA repair, Negative regulation of mRNA metabolic process, and Negative regulation of peptidase activity. Each is linked with PPP1R16B in more than 7 cancer types. Because this analysis shows association rather than direction, both PPP1R16B-to-partner and partner-to-PPP1R16B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by PPP1R16B-low versus PPP1R16B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R16B→partner) and Y-score (partner→PPP1R16B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of DNA repair →	+0.076	+1.339	<.001	.006	3	8
SOFT_TISSUE	Negative regulation of mRNA metabolic process →	+0.093	+1.035	<.001	.002	3	8
BLOOD_Lymphoma	Negative regulation of peptidase activity →	-0.519	-2.482	.002	<.001	3	8
BONE	Nerve development →	-0.071	-1.451	.001	<.001	3	8
BLOOD_Lymphoma	Positive regulation of DNA recombination →	+0.064	+2.330	<.001	<.001	3	7
OVARY	Positive regulation of double-strand break repair via homologous recombination →	+0.066	+0.718	<.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,610 associations by consensus.

Positive regulation of DNA repair by PPP1R16B expression — BONE

Explore this box plot interactively →