PPP1R16A

Across TCGA patient cohorts, PPP1R16A protein abundance is significantly associated with the RNA expression of many other genes, with 3,921 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPP1R16A-associated genes across cancer lineages are UNC5A, THEM6, and MAL2. Each is linked with PPP1R16A in more than 2 cancer types. Because this analysis shows association rather than direction, both PPP1R16A-to-partner and partner-to-PPP1R16A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP1R16A versus UNC5A in OV, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R16A→partner) and Y-score (partner→PPP1R16A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	UNC5A →	+1.156	+0.434	.002	.001	3	3
OV	THEM6 →	+1.026	+0.610	.001	<.001	3	3
OV	MAL2 →	+0.992	+0.534	.007	.001	3	3
OV	COX6C →	+0.517	+0.358	.008	.005	3	3
OV	GPT →	+1.120	+0.513	<.001	<.001	3	3
OV	C8orf33 →	+0.570	+0.367	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,921 associations by consensus.

PPP1R16A vs UNC5A — OV

Explore this scatter interactively →