PPP1R16A

Across TCGA patient cohorts, PPP1R16A mutation is significantly associated with the RNA expression of many other genes, with 216 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP1R16A-associated genes across cancer lineages are OFD1P2Y, CYMP-AS1, and RNU6-176P. Each is linked with PPP1R16A in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R16A-to-partner and partner-to-PPP1R16A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OFD1P2Y grouped by PPP1R16A-low versus PPP1R16A-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R16A→partner) and Y-score (partner→PPP1R16A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	OFD1P2Y →	+0.033	+5.087	<.001	.002	3	2
COAD	CYMP-AS1 →	+0.353	+4.233	<.001	.001	3	2
COAD	RNU6-176P →	+0.343	+3.665	<.001	.004	3	2
BLCA	RNA5SP488 →	+0.298	+3.363	.002	.004	3	2
BLCA	RNU6-1029P →	+0.175	+3.495	.005	.006	3	2
SARC	RN7SL700P →	+0.188	+5.345	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 216 associations by consensus.

OFD1P2Y by PPP1R16A expression — COAD

Explore this box plot interactively →