PPP1R16A

Across TCGA patient cohorts, PPP1R16A mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP1R16A-associated genes across cancer lineages are MPP, Pericytes, and MEP. Each is linked with PPP1R16A in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R16A-to-partner and partner-to-PPP1R16A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MPP grouped by PPP1R16A-low versus PPP1R16A-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R16A→partner) and Y-score (partner→PPP1R16A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MPP →	+0.029	+2.233	<.001	.045	3	2
SKCM	Pericytes →	+0.049	+2.269	.044	.021	3	1
UCEC	MEP →	+0.038	+3.332	.008	.005	3	1
UCEC	Class-switched memory B-cells →	-0.062	-3.321	.040	.010	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

MPP by PPP1R16A expression — COAD

Explore this box plot interactively →