PPP1R16A

Across TCGA cell cohorts, PPP1R16A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,141 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PPP1R16A-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Actomyosin contractile ring assembly actin filament organization, and Protein linear polyubiquitination. Each is linked with PPP1R16A in more than 12 cancer types. Because this analysis shows association rather than direction, both PPP1R16A-to-partner and partner-to-PPP1R16A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by PPP1R16A-low versus PPP1R16A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R16A→partner) and Y-score (partner→PPP1R16A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pre-mRNA catabolic process →	+0.216	+1.481	<.001	<.001	3	13
STOMACH	Actomyosin contractile ring assembly actin filament organization →	+0.186	+0.954	.001	.001	3	12
BREAST	Protein linear polyubiquitination →	+0.131	+1.439	.001	<.001	3	11
BONE	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.196	+1.729	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.153	+0.882	<.001	<.001	3	11
URINARY_TRACT	Methylglyoxal metabolic process →	+0.119	+0.734	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,141 associations by consensus.

Pre-mRNA catabolic process by PPP1R16A expression — BONE

Explore this box plot interactively →