PPP1R16A

Across TCGA cell cohorts, PPP1R16A mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PPP1R16A-associated genes across cancer lineages are ACOD1, LY6G6D, and DCANP1. Each is linked with PPP1R16A in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R16A-to-partner and partner-to-PPP1R16A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACOD1 grouped by PPP1R16A-low versus PPP1R16A-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R16A→partner) and Y-score (partner→PPP1R16A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ACOD1 →	+0.006	+4.867	<.001	.009	3	1
SKIN	LY6G6D →	+0.085	+4.273	.007	.006	3	1
SKIN	DCANP1 →	+0.006	+4.467	.007	.004	3	1
LUNG_SCLC	OR4F4 →	+0.016	+5.643	<.001	.002	3	1
LUNG_SCLC	DEFB125 →	+0.086	+5.643	<.001	.002	3	1
LUNG_SCLC	OR4F5 →	+0.013	+5.029	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

ACOD1 by PPP1R16A expression — BLOOD_Lymphoma

Explore this box plot interactively →