PPP1R15B

Across TCGA patient cohorts, PPP1R15B RNA expression is significantly associated with the protein abundance of many other proteins, with 9,668 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPP1R15B-associated proteins across cancer lineages are RPRD2, BROX, and ADAR. Each is linked with PPP1R15B in more than 6 cancer types. Because this analysis shows association rather than direction, both PPP1R15B-to-partner and partner-to-PPP1R15B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP1R15B versus RPRD2 in HNSC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R15B→partner) and Y-score (partner→PPP1R15B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RPRD2 →	+0.338	+0.421	<.001	<.001	3	7
LUAD	BROX →	+0.397	+0.415	<.001	<.001	3	5
LSCC	ADAR →	+0.281	+0.395	<.001	<.001	3	5
LUAD	C1orf35 →	+0.425	+0.565	<.001	<.001	3	5
LSCC	DBR1_S514 →	+0.475	+0.339	<.001	<.001	3	5
LSCC	DHX9 →	+0.262	+0.338	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,668 associations by consensus.

PPP1R15B vs RPRD2 — HNSC

Explore this scatter interactively →