PPP1R14B

Across TCGA patient cohorts, PPP1R14B protein abundance is significantly associated with the RNA expression of many other genes, with 5,504 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PPP1R14B-associated genes across cancer lineages are CXCL8, CBX7, and PFKFB4. Each is linked with PPP1R14B in more than 4 cancer types. Because this analysis shows association rather than direction, both PPP1R14B-to-partner and partner-to-PPP1R14B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP1R14B versus CXCL8 in CCRCC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R14B→partner) and Y-score (partner→PPP1R14B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	CXCL8 →	+2.245	+0.229	<.001	<.001	3	5
BRCA	CBX7 →	-0.716	-0.374	<.001	<.001	3	4
UCEC	PFKFB4 →	+0.823	+0.325	<.001	<.001	3	4
UCEC	SLC2A1 →	+1.082	+0.350	<.001	<.001	3	4
LUAD	PAICS →	+0.668	+0.417	<.001	<.001	3	4
LUAD	ZNF540 →	-0.508	-0.272	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,504 associations by consensus.

PPP1R14B vs CXCL8 — CCRCC

Explore this scatter interactively →