PPP1R14B

Across TCGA patient cohorts, PPP1R14B mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP1R14B-associated genes across cancer lineages are RNA5SP534, TRAJ25, and NMTRQ-TTG12-1. Each is linked with PPP1R14B in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R14B-to-partner and partner-to-PPP1R14B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP534 grouped by PPP1R14B-low versus PPP1R14B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R14B→partner) and Y-score (partner→PPP1R14B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP534 →	+0.665	+5.242	<.001	.007	3	1
UCEC	TRAJ25 →	+0.846	+5.551	<.001	.004	3	1
UCEC	NMTRQ-TTG12-1 →	+0.746	+5.358	<.001	.006	3	1
UCEC	RNU6-794P →	+0.846	+6.453	<.001	.001	3	1
STAD	RNU1-57P →	+0.382	+4.026	<.001	.002	3	1
STAD	RNU6-63P →	+0.626	+3.838	.004	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

RNA5SP534 by PPP1R14B expression — UCEC

Explore this box plot interactively →