PPP1R14B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PPP1R14B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,649 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PPP1R14B-associated GO terms across cancer lineages are Fatty acid metabolic process, Regulation of metaphase plate congression, and Regulation of attachment of mitotic spindle microtubules to kinetochore. Each is linked with PPP1R14B in more than 11 cancer types. Because this analysis shows association rather than direction, both PPP1R14B-to-partner and partner-to-PPP1R14B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fatty acid metabolic process grouped by PPP1R14B-low versus PPP1R14B-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R14B→partner) and Y-score (partner→PPP1R14B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PANCREASFatty acid metabolic process →-0.051-0.806<.001<.001312
CNSRegulation of metaphase plate congression →+0.111+0.809<.001<.001312
UPPER_AERODIGESTIVE_TRACTRegulation of attachment of mitotic spindle microtubules to kinetochore →+0.142+0.749.007.008311
UPPER_AERODIGESTIVE_TRACTPositive regulation of attachment of mitotic spindle microtubules to kinetochore →+0.151+0.798.008.006311
PANCREASMitotic spindle midzone assembly →+0.213+0.682.002.007310
LIVERProtein localization to microtubule plus-end →+0.179+0.673<.001.006310
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,649 associations by consensus.

Fatty acid metabolic process by PPP1R14B expression — PANCREAS

Box plot of Fatty acid metabolic process in PPP1R14B-low vs PPP1R14B-high samples in PANCREAS.

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Exploration