PPP1R14B-AS1

Across TCGA pan-cancer cohorts, PPP1R14B-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated PPP1R14B-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher PPP1R14B-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PPP1R14B-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and ESCA show a favorable association.

UVM, KIRC, and KICH are the cancer types where PPP1R14B-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.393	0.784	<.001	141	view →
KIRC	OS	Tertile	All	0.525	0.721	<.001	84	view →
KICH	OS	Median	II,III,IV	0.770	1.000	<.001	80	view →
SKCM	DFS	Median	All	0.515	0.745	<.001	68	view →
LIHC	OS	Median	All	0.587	0.777	<.001	54	view →
LGG	DFS	Median	All	0.671	0.809	<.001	52	view →
HNSC	DFS	Tertile	III,IV	0.267	0.411	.001	48	view →
LUAD	DFS	Median	All	0.587	0.737	<.001	46	view →
UCS	DFS	Median	III,IV	0.569	0.273	.008	42	view →
ACC	DFS	Quartile	All	0.223	0.686	.003	37	view →
CESC	OS	Tertile	II,III,IV	0.443	0.831	.003	34	view →
GBM	DFS	Tertile	All	0.170	0.440	.001	25	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

PPP1R14B-AS1–UVM (DFS)

Open the UVM breakdown →