PPP1R14B-AS1

Across TCGA pan-cancer cohorts, PPP1R14B-AS1 RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of PPP1R14B-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where PPP1R14B-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PPP1R14B-AS1 is over-expressed in tumor.

COAD, LUSC, and LUAD are the cancer types where PPP1R14B-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PPP1R14B-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	+1.816	<.001	11	view →
LUSC	All	III,IV	+2.995	<.001	9	view →
LUAD	Female	III,IV	+2.600	<.001	9	view →
THCA	Male	All	+0.844	<.001	9	view →
BLCA	Male	III,IV	+2.639	<.001	8	view →
LIHC	Female	II,III,IV	+1.271	<.001	8	view →
KIRC	All	All	+0.475	.001	7	view →
UCEC	All	II,III,IV	+2.283	<.001	6	view →
BRCA	All	III,IV	+1.334	<.001	6	view →
KIRP	All	All	+0.983	<.001	6	view →
CHOL	All	All	+1.828	<.001	5	view →
STAD	All	IV	+1.683	.005	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

PPP1R14B-AS1–COAD

Open the COAD breakdown →