PPP1R13L

Across TCGA pan-cancer cohorts, PPP1R13L mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated PPP1R13L data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher PPP1R13L mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated PPP1R13L expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCEC show a favorable association.

CCRCC, HNSC, and PDAC are the cancer types where PPP1R13L mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	All	0.613	0.915	.009	21	view →
HNSC	DFS	Tertile	III,IV	1.000	0.897	.019	19	view →
PDAC	DFS	Median	IV	0.214	0.785	.006	19	view →
UCEC	OS	Median	All	0.983	0.854	.014	10	view →
GBM	OS	Median	All	0.626	0.430	.001	7	view →
LSCC	OS	Quartile	All	0.751	0.945	.030	3	view →
LUAD	OS	Quartile	II,III,IV	0.320	0.800	.024	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

PPP1R13L–CCRCC (DFS)

Open the CCRCC breakdown →