PPP1R13L

Across TCGA patient cohorts, PPP1R13L mutation is significantly associated with the RNA expression of many other genes, with 1,790 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP1R13L-associated genes across cancer lineages are SH3GL1, OR2BH1P, and FEN1. Each is linked with PPP1R13L in more than 2 cancer types. Because this analysis shows association rather than direction, both PPP1R13L-to-partner and partner-to-PPP1R13L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SH3GL1 grouped by PPP1R13L-low versus PPP1R13L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R13L→partner) and Y-score (partner→PPP1R13L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SH3GL1 →	+0.415	+2.566	<.001	<.001	3	3
SKCM	OR2BH1P →	+0.012	+4.225	<.001	.005	3	2
SKCM	FEN1 →	+0.550	+2.591	.007	.006	3	2
SKCM	WSB2 →	+0.513	+3.207	.005	.009	3	2
UCEC	BRI3BP →	+0.531	+2.963	.001	<.001	3	2
SKCM	NEMP2 →	+0.633	+2.616	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,790 associations by consensus.

SH3GL1 by PPP1R13L expression — UCEC

Explore this box plot interactively →