PPP1R13L

Across TCGA patient cohorts, PPP1R13L mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP1R13L-associated genes across cancer lineages are eEF2, PCNA, and eIF4E. Each is linked with PPP1R13L in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R13L-to-partner and partner-to-PPP1R13L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by PPP1R13L-low versus PPP1R13L-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R13L→partner) and Y-score (partner→PPP1R13L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	eEF2 →	+0.351	+3.321	.040	.010	3	2
SKCM	PCNA →	+0.199	+3.321	.048	.010	3	2
UCEC	eIF4E →	+0.172	+3.183	.026	.009	3	2
UCEC	MSH6 →	-0.441	-2.807	<.001	.002	3	2
UCEC	p62 Lck ligand →	+0.312	+1.847	.008	.008	3	2
UCEC	Annexin-1 →	+0.668	+3.807	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

eEF2 by PPP1R13L expression — SKCM

Explore this box plot interactively →