PPP1R13B

Across TCGA pan-cancer cohorts, PPP1R13B mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated PPP1R13B data layer compared with 22 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher PPP1R13B mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated PPP1R13B expression acts as an unfavorable survival marker, although some lineages such as LSCC and PDAC show a favorable association.

LSCC, PDAC, and GBM are the cancer types where PPP1R13B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Median	II,III,IV	0.870	0.583	.009	19	view →
PDAC	OS	Tertile	III,IV	0.974	0.303	.002	19	view →
GBM	OS	Tertile	All	0.531	0.259	.015	7	view →
CCRCC	DFS	Tertile	III,IV	0.725	0.426	.031	5	view →
LUAD	OS	Tertile	II,III,IV	1.000	0.437	.014	5	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

PPP1R13B–LSCC (OS)

Open the LSCC breakdown →