PPP1R13B

Across TCGA patient cohorts, PPP1R13B mutation is significantly associated with the RNA expression of many other genes, with 2,704 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP1R13B-associated genes across cancer lineages are HSPD1P18, HMGN2P32, and RPL12P48. Each is linked with PPP1R13B in more than 2 cancer types. Because this analysis shows association rather than direction, both PPP1R13B-to-partner and partner-to-PPP1R13B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HSPD1P18 grouped by PPP1R13B-low versus PPP1R13B-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R13B→partner) and Y-score (partner→PPP1R13B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HSPD1P18 →	+0.128	+5.241	.001	.007	3	3
COAD	HMGN2P32 →	+0.663	+3.852	.001	.003	3	3
READ	RPL12P48 →	+0.201	+4.023	.005	.005	3	2
SARC	MTCYBP40 →	+0.050	+6.152	<.001	.001	3	2
SARC	ECM1P2 →	+0.035	+5.005	.002	.009	3	2
SARC	MIR3912 →	+0.424	+5.005	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,704 associations by consensus.

HSPD1P18 by PPP1R13B expression — HNSC

Explore this box plot interactively →