PPP1R13B

Across TCGA cell cohorts, PPP1R13B mutation is significantly associated with the RNA expression of many other genes, with 909 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PPP1R13B-associated genes across cancer lineages are GHRHR, MYF5, and CDY2A. Each is linked with PPP1R13B in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R13B-to-partner and partner-to-PPP1R13B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GHRHR grouped by PPP1R13B-low versus PPP1R13B-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R13B→partner) and Y-score (partner→PPP1R13B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	GHRHR →	+0.372	+4.420	<.001	<.001	3	1
BLOOD_Lymphoma	MYF5 →	+0.006	+3.662	<.001	.009	3	1
BLOOD_Lymphoma	CDY2A →	+0.002	+3.662	<.001	.009	3	1
SOFT_TISSUE	OR4X2 →	+0.032	+5.369	<.001	.004	3	1
SOFT_TISSUE	PRR20B →	+0.043	+5.977	<.001	.001	3	1
SOFT_TISSUE	PRR20A →	+0.043	+5.977	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 909 associations by consensus.

GHRHR by PPP1R13B expression — BLOOD_Lymphoma

Explore this box plot interactively →